Routes for MLS ASCP: Which One is Your Relevant?
The American Society for Clinical Pathology (ASCP) Board of Certification (BOC) determines many routes for the MLS ASCP.
What are the means of routes?
The routes are the set of documentation that you must achieve to apply for the MLS ASCP exam.
Here, we will briefly describe the routes for the MLS ASCP exam that the ASCP BOC suggests.
Routes for MLS ASCP
The ASCP Board of Certification is the credential body that offers certificates worldwide to U.S. and foreign candidates.
The certification that is designed for United States applicants is mentioned with the ASCP symbol and for international candidates with ASCPi.
Here, you will get information about the routes for MLS ASCP/ASCPi;
Routes for MLS ASCP: United States Professionals
The board fixed 6 routes for the MLS ASCP, you are liable to satisfy at least one.
First Route
- Baccalaureate degree from authentic educational institutions
- Complete an MLS (medical lab scientist) program by NAACLS accredited.
Second Route
- A valid license of ASCP MLT (medical laboratory technician)
- Clinical experience in chemistry, microbiology, urinalysis/other body fluids, immunology, hematology, blood banking, and lab operation (this experience must be of 2 years)
- Bachelor’s degree (it must be obtained with a combination of 16 semester hours in chemistry and biology, including one semester hrs in organic/biochemistry and microbiology).
Third Route
- The Board has sealed its eligibility requirements (CLA ASCP). For now, there are no determined requirements for it.
Fourth Route
- Clinical experience of five years in hematology, microbiology, blood banking, and other related fields.
- Baccalaureate degree from an approved institution with 16 semesters hrs in chemistry (one semester hr in biochemistry/organic) and 16 semester hrs in biology (one semester hrs in microbiology).
Fifth Route
- A valid license of MLS (ASCPi)
- 5 years of experience (clinical) in microbiology, blood banking, chemistry, and other required fields.
- Transcript evaluation
Sixth Route
- Medical lab training program (50 weak) from the U.S. military.
- 1 year of clinical experience in recommended areas
- Baccalaureate degree (16 semester hrs (24 quarter hrs) in chemistry & biology (including one semester hr in microbiology))
Routes for MLS ASCPi: Foreign Lab Professionals
5 routes for MLS ASCPi, make sure to go with one to apply for a certificate.
First Route
- Bachelor's degree that must be in biological science/medical lab science/chemistry.
- MLS training program (chemistry, hematology, microbiology, and bloos banking)
Second Route
- Baccalaureate degree (must be in medical laboratory science)
- Clinical experience in hematology, chemistry, blood bank, & microbiology (three years of experience)
Third Route
- Bachelor’s degree from an accredited college/university
- MLS (medical lab science) program in chemistry, blood bank, hematology, and microbiology (program must be of two years)
Fourth Route
- Baccalaureate degree in chemistry/biological science from an education institution (approved)
- Clinical experience from an authorized lab in blood bank (immunohematology), microbiology, chemistry, and hematology (make sure to obtain five years of experience).
Fifth Route
- Make sure to earn a bachelor's degree from an accredited educational institution.
- Diploma in chemistry/biological science from an authorized educational institution (diploma must be of 2 years).
- Clinical experience that must be obtained of five years in hematology, blood bank (immunohematology), microbiology, and chemistry.

Abdelhalim Elshawadfy is an ASCP certified Medical Laboratory Scientist (MLS ASCP), Specialist in Microbiology (SM ASCP), and Molecular Biology Technologist (MB ASCP) with a distinguished career marked by expertise, continuous learning, and a commitment to elevating the standards of clinical laboratory science. As an ASCP Certification Expert and American Board Certification Expert, Abdelhalim Elshawadfy continues to make invaluable contributions to the field, leaving a lasting impact on the medical community.
