ASCP MLS Content Outlines: Main Topics to Cover
Understanding the ASCP MLS content outlines is integral to covering the exam content area and passing the exam successfully.
The ASCP Board of Certification describes the entire content topics in the ASCP MLS content guidelines.
Information regarding the subject name, main topics, key topics, and percentage of questions are all described in the ASCP MLS content guidelines
The American Society for Clinical Pathology (ASCP) Board of Certification (BOC) is very viable in its responsibilities.
Therefore, it provides all necessary information regarding preparation, exam content areas, eligibility requirements, etc., that are relevant for professionals for exam.
Whether your aim is to achieve the ASCP certification, or you are struggling for recertification, you will get all the crucial resources possible to achieve success in your mission.
Here, we are going to highlight all the ASCP MLS content outlines, you must check them clearly to cover the entire content.
ASCP MLS Content Outlines: Overview of Content
The ASCP Board of Certification clearly mentions all the outlines of each content area.
The following are outlines for all the exam content areas
ASCP MLS Content Outlines for Blood Banking
- Blood products
- Physiology & pathophysiology
- Blood group systems
- Transfusion practice
- Blood group immunology,
- Serologic & molecular testing
ASCP MLS Content Outlines for Hematology
- Physiology
- Disease states
- Hemostasis (including lab determinations, physiology, disease states)
- Laboratory testing
MLS ASCP Content Outlines for Immunology
- Principles of immunology
- Transplantation
- Test results
- Infectious disease serology
- Serologic procedures
- Diseases of the immune system
ASCP MLS Content Outlines for Microbiology
- Preanalytic procedures
- Analytic procedures for bacteriology
- Analytic procedures for parasitology, mycobacteriology, virology, and mycology
- Postanalytic procedures
ASCP MLS Content Outlines for Lab Operation
- Safety
- Lab Mathematics
- Instrumentation
- Basic management principles
- Manual/automated methodology
- Education principles
- Quality assessment/troubleshooting
MLS ASCP Content Outlines for Urinalysis and Other Body Fluids
- Physical Testing
- Physiology
- Disease states
- Microscopic analysis
- Chemical testing
ASCP MLS Content Outlines for Chemistry
- Carbohydrates
- Lipids
- Therapeutic drug monitoring
- Heme derivatives
- Enzymes
- Electrolytes
- Acid-base determinations ( blood gases, etc)
- Endocrinology
- Vitamins & Nutrition
- Toxicology
- Proteins/other nitrogen-containing compounds
FAQs for the MLS ASCP Content Outlines
Which content exam area does the ASCP Board of Certification recommend for the ASCP medical lab scientist exam preparation?
The ASCP Board of Certification (BOC) determines 7 subjects for ASCP MLS exam preparation: Microbiology, Hematology, Chemistry, Immunology, Blood Banking, and Urinalysis/other Body Fluids.
MLSIAcademy.com is an outstanding academy that offers all the tools necessary to cover the ASCP MLS content outlines and it designs these products according to the outlines.
No, if you apply the right tools at the right place and right time, you can cover the entire exam content area easily.
Resources: ASCP BOC.

Abdelhalim Elshawadfy is an ASCP certified Medical Laboratory Scientist (MLS ASCP), Specialist in Microbiology (SM ASCP), and Molecular Biology Technologist (MB ASCP) with a distinguished career marked by expertise, continuous learning, and a commitment to elevating the standards of clinical laboratory science. As an ASCP Certification Expert and American Board Certification Expert, Abdelhalim Elshawadfy continues to make invaluable contributions to the field, leaving a lasting impact on the medical community.
