MLS ASCP Study Guide Review and the Best All in One Solution

Studying for MLS ASCP certification had never been easy. This is why The American Society of Clinical Pathology (ASCP) Board of Certification (BOC) has produced the MLS ASCP study guide.

To choose MLS ASCP certified, BOC conducts a specific analytical Computer Adaptive Test (CAT) to recognize the candidates' knowledge and skill in microbiology, laboratory operation, chemistry, hematology, blood bank, and urinalysis.

MLS certification candidates can use the study guide to know the examination syllabus and which subject areas they should focus on in detail to start exam preparation.

In this article, we are going to review the MLS ASCP study guide of the ASCP BOC and the best all-in-one MLS ASCP/ASCPi study material by MLSIA that has been structured and compiled based on that guide.

What is MLS ASCP Study Guide?

It’s a study guide made by the ASCP BOC certification exam of both US and international candidates that covers all the exam content areas and helps applicants to know about the informative exam syllabus. 

MLS ASCP Study Guide covers blood bank, chemistry, urinalysis and other body fluid, microbiology, immunology, hematology, and laboratory operation content area.

ASCP MLS exam comprised 100 multiple questions with each best answer and candidates have to cover all questions in a given 2-hour 30-minute time frame.

Chemistry Study Guide for MLS (ASCP) and MLS(ASCPi)

The chemistry content area comprises enzymes, vitamins, nutrition, electrolytes, heme derivative, protein and other nitrogen-containing compounds, carbohydrates, acid-base determinations (including blood gasses), lipids, therapeutic drugs, endocrinology, toxicology, and monitoring. Chemistry covers 17-22% of exam questions.

The BOC divided chemistry study areas into four-part including general chemistry, proteins and enzymes, acid-base, blood gases, and electrolytes, and special chemistry.

General Chemistry

General Chemistry has three categories: Carbohydrates, Lipids, and Heme Derivatives

Carbohydrates

• Biochemical theory and physiology comprise Physical and chemical properties, Metabolic pathways, and Normal and abnormal states.
• Test procedures include Glycated proteins, specimen collection and processing, Tolerance testing, Principles and Special precautions, interfering substances, and troubleshooting
• Test result interpretation
• Disease state correlation

Lipids

• Biochemical theory and physiology: Normal and abnormal states, Physical and chemical properties (Phospholipid, Lipoproteins, Cholesterol, Apolipoproteins, and Triglycerides, and. Metabolic pathways.)
• Test procedures: Principles, Specimen collection and processing, Special precautions, interfering, Substances, and troubleshooting.
• Test result interpretation
• Disease state correlation.

Heme Derivatives

• Biochemical theory and physiology: Physical and chemical properties (Bilirubin, Hemoglobin, Myoglobin, Porphyrins, and  Urobilinogen), Metabolic pathways, and Normal and abnormal states.
• Test procedures: Principles, Specimen collection and processing, Special precautions, interfering, Substances, and troubleshooting.
• Test result interpretation
• Disease state correlation

Proteins And Enzymes

It divides into two parts: Enzymes and Proteins and Other Nitrogen-Containing Compounds.

Enzymes

This part of chemistry comprises:

• Biochemical theory and physiology: Normal and abnormal states, Metabolic pathways, and Physical and chemical properties (Alkaline, Phosphatase, Amylase, Lipase, Angiotensin-converting enzyme, LD, GGT, AST/ALT, and  CK) and Normal and abnormal states.
• Test procedures include Principles, Specimen collection and processing, Special precautions, interfering, Substances, and troubleshooting.
• Test result interpretation
• Disease state correlation

Proteins and Other Nitrogen-Containing Compounds

• Biochemical theory and physiology contain Physical and chemical properties (Proteins, Urea, Tumor markers, Amino acids, Creatinine, Uric acid, Cardiac markers and Ammonia), Normal and abnormal states, and metabolic pathways.
• Test procedures include Principles, Clearances, Specimen collection and processing, Special precautions, interference, Substances, and troubleshooting
• Test result interpretation
• Disease state correlation

Acid-Base, Blood Gases, And Electrolytes

This content area of chemistry is divided into two parts: Acid-Base Determinations (Including Blood Gases)(H4 tag and Electrolytes.

Acid-Base Determinations (Including Blood Gases)

• Biochemical theory and physiology; CO2 and O2 transport, Normal and abnormal states, Henderson-Hasselbach equation, and pH and H+ion concentration.
• Test procedures: Specimen collection and processing, Special precautions, interfering, Substances, and troubleshooting, and Analytical principles.
• Test result interpretation
• Disease state correlation

Electrolytes

• Biochemical theory and physiology include: magnesium Calcium, phosphorus, TIBC, and iron, Potassium, Sodium, CO2, chloride, and bicarbonate, Normal and abnormal states and Trace elements.
• Test procedures: Specimen collection and processing, Special precautions, interfering, Substances, and troubleshooting, Principles.
• Calculations ( anion gap, osmolality)
• Test result interpretation
• Disease state correlation

Special Chemistry

Special Chemistry content areas are divided into four parts. Endocrinology, Vitamins and Nutrition, Therapeutic Drug Monitoring, and Toxicology.

Endocrinology

• Biochemical theory and physiology: Mechanism of action, Metabolic pathways, Normal and abnormal states and Physical and chemical properties (Catecholamine, Steroid hormones (e.g., cortisol, estrogen, hCG), Thyroid hormones, and Peptide hormones (e.g., insulin, prolactin).
• Test procedures: Principles (Immunoassay and Fluorescence) and Stimulation/suppression tests and Specimen collection and processing, Special precautions, interfering, Substances, and troubleshooting.
• Test result interpretation
• Disease state correlation

Vitamins and Nutrition

• Biochemical theory and physiology; Normal and abnormal states, Metabolism and action and Properties.
• Test procedures: specimen collection and processing, Special precautions, interfering substances, and troubleshooting, and Principles.
• Test result interpretation
• Disease state correlation

Therapeutic Drug Monitoring

• Pharmacokinetics: Toxic states, Metabolism and excretion, and Therapeutic states.
• Chemical and physical properties: Cardioactive (e.g., digoxin), Aminoglycosides (e.g., gentamicin), Immunosuppressants (e.g., tacrolimus), Anticonvulsants (e.g., phenobarbital) and Antidepressants (e.g., lithium).
• Test procedures: specimen collection and processing, Special precautions, interfering substances, troubleshooting, and Principles (Immunoassay)
• Test result interpretation
• Disease state correlation

Toxicology

• Toxicokinetics: Metabolism and excretion, Toxic effects, symptoms, and signs.
• Chemical and physical properties: Drugs of abuse, Heavy metals (e.g., lead), Alcohols, and Analgesics (e.g., acetaminophen).
• Test procedures: Principles (Immunoassay, Enzymatic methods), specimen collection and processing, Special precautions, interfering substances, and troubleshooting.
• Test result interpretation
• Disease state correlation

Microbiology Study Guide For MLS (ASCP) and MLS(ASCPi)

Microbiology is divided into four parts: Preanalytic Procedures, Analytic Procedures for Bacteriology, Analytic Procedures for Mycobacteriology, Virology, Parasitology and Mycology, and Post analytic Procedure. BOC opt 17-22% question from this part.

Preanalytic Procedures

It divides into three parts:

Specimen Collection and Transport

It is related to Specimen transport systems and conditions for all organisms, Specimen collection, and Patient identification and specimen labeling.

Specimen Processing

Specimen Processing comprises Incubation conditions (e.g., temperature, atmosphere, and duration), Biosafety cabinet and personal protective equipment, Specimen prioritization, and rejection criteria, Media, Inoculation of media, Specimen preparation methods and applications, and Preparation methods for slides used for stains.

Stains: Procedure, Principle, and Interpretation

Acid-fast, Modified acid-fast, Giemsa, Gram, Trichrome, KOH and calcofluor-white, and Acridine orange.

Analytic Procedures For Bacteriology

This content area is divided into the following parts

Blood and Bone Marrow

Specimen sources (e.g., intravenous catheters peripheral,), Rapid identification/resistance detection methods, Organism pathogenicity (e.g., etiology, virulence mechanisms, transmission), Colony morphology and identification of major pathogens (e.g., Staphylococcus aureus, other Staphylococcus spp. including beta-hemolytic streptococci, coagulase-negative staphylococci, Enterococcus spp, Candida spp., Streptococcus pneumoniae,  Enterobacteriaceae, Acinetobacter baumannii, Pseudomonas spp.), Common agents of endocarditis, Continuous-monitoring systems, Agents of bone marrow infection (e.g., Brucella spp., Salmonella spp.) and Species comprising skin flora and clinical significance.

Cerebrospinal Fluid

Organism pathogenicity (e.g., etiology, transmission, virulence mechanisms), Colony morphology and identification of major pathogens associated with acute meningitis (e.g., Haemophilus influenzae, Streptococcus pneumoniae, Neisseria meningitidis, Listeria monocytogenes, Enterobacteriaceae,, beta-hemolytic streptococci, Escherichia coli, and Staphylococcus aureus ), Specimen sources (e.g., lumbar puncture, shunt, reservoir), Correlation with other laboratory results (e.g., glucose, protein, cell count), Direct detection and molecular methods, and  Common agents of shunt infections (e.g., other Staphylococcus spp. including coagulase-negative staphylococci,  Propionibacterium spp., Corynebacterium spp., Cutibacterium spp.)

Body Fluids from Normally Sterile Sites

Specimen sources (e.g., pericardial, pleural, peritoneal, synovial, amniotic vitreous, and aqueous humor,), Indigenous organisms associated with mucosal surfaces and skin,  Colony morphology and identification of major pathogens (e.g., Escherichia coli, Streptococcus pneumoniae, Neisseria spp., Haemophilus influenzae, Listeria monocytogenes, Enterobacteriaceae, Staphylococcus aureus, Acinetobacter spp., beta-hemolytic streptococci, Enterococcus spp., Pseudomonas aeruginosa, Clostridium perfringens, Bacteroides fragilis group),Organism pathogenicity (e.g., transmission, virulence mechanisms, etiology) and Molecular methods. 

Lower Respiratory 

Organism pathogenicity (e.g., etiology, virulence mechanisms, transmission),  Colony morphology and identification of major pathogens, Specimen sources (e.g., sputum, endotracheal aspirate, bronchial wash, bronchial brush, bronchoalveolar lavage), Direct detection and molecular methods (e.g., Streptococcus pyogenes, Bordetella pertussis),  Significance of quantitative and semiquantitative reporting of results and Species comprising oral flora colony and Gram stain morphology. 

Upper Respiratory

Direct detection and molecular methods (e.g., Bordetella pertussis, Streptococcus pyogenes,), Organism pathogenicity (e.g., transmission, etiology,, virulence mechanisms), Specimen sources (e.g., throat, middle ear, nasopharynx,, sinus), Colony morphology and identification of major pathogens and Indigenous flora colony and Gram stain morphology.

Gastrointestinal

Serotyping of Escherichia coli, Shigella spp., and Salmonella spp, Colony morphology and identification of major pathogens (e.g., Salmonella spp., Shigella spp., Campylobacter spp., Yersinia enterocolitica, Aeromonas spp., Plesiomonas shigelloides., toxigenic Escherichia coli., Vibrio spp.,), Direct detection and molecular methods (e.g.,  Shiga toxin, Clostridioides difficile,), Detection methods for Helicobacter pylori and Organism pathogenicity (e.g., etiology, virulence mechanisms, transmission,).

Skin, Soft Tissue, and Bone

Colony morphology and identification of major pathogens, Specimen sources (e.g., wound, biopsy, abscess), Organism pathogenicity (e.g.,, transmission, etiology, virulence mechanisms), and  Indigenous flora colony and Gram stain morphology.

Genital Tract

Culture and/or molecular detection (e.g., Mycoplasma spp, Neisseria gonorrhoeae, Streptococcus agalactiae, and Chlamydia trachomatis), Indigenous organisms colony and Gram stain morphology, Specimen sources (e.g., endocervical, vaginal, urethral, cervical), Methods for detection of pathogens associated with vaginitis (e.g., Candida spp, Trichomonas vaginalis., bacterial vaginosis) and Organism pathogenicity (e.g., etiology, virulence mechanisms, transmission).

Urine

Correlation of colony counts with clinical significance, Correlation of culture with urinalysis results, Specimen sources (e.g., mid-stream cleancatch,  suprapubic, nephrostomy, catheterized), Colony morphology and identification of major urinary pathogens (e.g., Enterobacteriaceae, Enterococcus spp., Streptococcus agalactiae, Candida spp., Staphylococcus saprophyticus, Enterococcus spp.,)

Identification Methods (Theory, Interpretation, and Application) 

Colony morphology, Conventional biochemical identification (e.g., X and V factors,  Neisseria carbohydrate utilization), Commercial kits, Rapid tests used for presumptive identification (e.g., coagulase, catalase, oxidase, indole, PYR), Automated methods, Multiplex molecular methods, Sequencing (e.g., 16S), MALDI-TOF MS

Antimicrobial Susceptibility Testing and Antibiotic Resistance

Phenotypic detection of resistance (e.g., ESBL, Carbapenemases, beta-lactamase, inducible clindamycin resistance), Mechanisms of action of major antibiotic classes, Intrinsic resistance patterns for common species, Detection of genetic determinants of resistance (e.g., vanA, mecA, blaKPC), Method, theory, interpretation, and application.

MRSA/MSSA, VRE, ESBL/CRE Screening

Specimen sources, Molecular methods, and Culture methods

BSL-3 Pathogens and Select Agents (Bioterrorism)

Organism pathogenicity (e.g., etiology, transmission, virulence mechanisms), Specimen sources(e.g., blood, tissue, sputum, lymph node),  Role of regional laboratory and Laboratory Response Network, Colony morphology and rapid tests used for presumptive identification (e.g., Yersinia pestis, Bacillus anthracis, Brucella spp., Francisella tularensis) 

Analytic Procedures For Mycobacteriology, Virology, Parasitology, And Mycology

BOC divides this content area into four-part Mycobacteriology and Nocardia spp, Virology, Parasitology, and Mycology.

Mycobacteriology and Nocardia spp, Virology, Parasitology, and Mycology

Antimicrobial therapy, Specimen sources (e.g., lower respiratory, soft tissue, blood,), Identification methods (e.g., probes, MALDI-TOF MS, sequencing), Acid-fast reaction, colony morphology, and growth characteristics, Major pathogens and disease states (e.g., etiology, transmission, epidemiology), Organism pathogenicity (e.g., etiology, virulence mechanisms, transmission), and Direct detection by molecular methods.

Virology

Major pathogens and disease states (e.g., etiology, transmission, epidemiology), Specimen sources, and Direct detection of pathogens.

Parasitology

Direct and molecular detection, Major pathogens and disease states (e.g., epidemiology, transmission, etiology), Microscopic and macroscopic identification, and Specimen sources (e.g., stool, blood, respiratory, tissue) 

Mycology

Specimen sources, Microscopic identification of major pathogens, Major pathogens, and disease states (e.g., epidemiology, etiology, transmission), Direct and molecular detection, Colony morphology, and growth characteristics of major pathogens (e.g., temperature, length of incubation, growth rate,), and Other identification methods (e.g., MALDITOF MS, biochemical, automated methods,)

Postanalytic Procedures

Documentation Practices, Issuing Corrected Reports, Reporting to Infection Control/Prevention and Public Health, Urgent and Critical Value Reporting, and Result Review and Autoverification.

Hematology Study Guide For MLS(ASCP) and MLS(ASCPi)

BOC divide Hematology exam content into four part: Hematology Physiology (to include blood, body fluids, and bone marrow), hematology disease states, hematology laboratory testing, and hemostasis. 17-22% of exam questions come from Hematology.

Hematology Physiology (to include blood, body fluids, and bone marrow)

It is about destruction, Function, and Production 

Hematology Disease States

Hematology disease states divide into Erythrocytes, Leukocytes (WHO classification), and Platelets.

Erythrocytes

• Anemia

Microcytic (Sideroblastic, Chronic inflammation, Iron deficiency Thalassemia), Normocytic (Acquired hemolytic, Acute hemorrhage, Hereditary hemolytic and Hypoproliferative), Macrocytic (Non-megaloblastic and Megaloblastic), Hemoglobinopathies

• Erythrocytosis 

Absolute and Relative 

Leukocytes (WHO classification)

• Benign leukocyte disorders 

Lymphoid and Myeloid

• Myeloid neoplasia

Myelodysplastic syndromes, Myeloproliferative neoplasms, and Acute leukemia

• Lymphoid neoplasia

Plasma cell dyscrasias, Acute leukemia, and Chronic leukemia/lymphoma

• Hereditary anomalies

Platelets

• Quantitative abnormalities

Thrombocytopenia (Pseudothrombocytopenia, Decreased production, Increased destruction (e.g., ITP, TTP, HIT)), and Thrombocytosis

• Qualitative defects

Glanzmann thrombasthenia, von Willebrand disease, and Bernard-Soulier syndrome

Hematology Laboratory Testing

BOC divide this content into the following part.

Cell Counts (to include blood and body fluids)

Automated, Manual, Reticulocytes, and Spurious results

Differentials and Morphology Evaluation

Hemoglobin

Quantitative, Qualitative (Electrophoresis, HPLC, and Sickle solubility)

Hematocrit

Indices 

Hemolytic Indicators (e.g., haptoglobin, LD)

Special Stains

Myeloperoxidase, Prussian blue, Esterase, and Kleihauer-Betke

Other Studies 

ESR, Heinz body, and G-6-PD

Flow Cytometry Immunophenotyping

Leukemia, Lymphocyte subsets, Lymphoma, and PNH

Molecular and Cytogenetic Testing

Recurring cytogenetic abnormalities (WHO classification), BCR/ABL1 and JAK2

HEMOSTASIS

It is divided into three categories: Physiology, Disease States, and Laboratory Determinations.

Physiology

Fibrinolytic pathway, Coagulation pathways, and Vascular system

Disease States

Inhibitors, Hypercoagulable states, DIC, Coagulation factor deficiencies(Acquired and hereditary), and Fibrinolytic system.

Laboratory Determinations

APTT, PT/INR, D-dimer, Fibrinogen, Mixing studies, Platelet function (e.g., PFA), Platelet aggregation, Inhibitor assays, Thrombin time, von Willebrand assays, Hypercoagulability assessment (Molecular (e.g., factor V Leiden, prothrombin 20210), Assays (e.g., lupus anticoagulant, protein S, protein C, HIT studies)), Thromboelastography, Factor assays, Direct thrombin inhibitors, Anti-Xa, and Heparin neutralization.

Blood Bank Study Guide For MLS (ASCP) and MLS(ASCPi)

BOC divides the Blood Bank study guide into six parts including Blood Products, Blood Group Systems, Blood Group Immunology, Physiology And Pathophysiology, Serologic And Molecular Testing, And Transfusion Practice. The BOC exam takes 17-22% of questions from the Blood Bank.

Blood Products

This part divides into the following parts:

Donors

Adverse reactions, Qualifications, Special donations (e.g., autologous), and Collection Methods

Processing

Labeling, and Testing 

Storage

Temperature requirements, Anticoagulants/additives, Properties of stored products, Expiration, and Transportation. 

Blood Components

Cryoprecipitated AHF, Plasma, Platelets, Red blood cells, Frozen/deglycerolized red blood cells, Leukocyte-reduced components, Whole blood, Granulocytes, Fractionation products, Washed red blood cells, Irradiated components, and Apheresis products.

Blood Component Quality Control

Blood Group Systems

It is divide into Genetics, Biochemistry/Antigens, and Role of Blood Groups in Transfusion.

Genetics

Basic, Inheritance of blood groups, and Molecular 

Biochemistry/Antigens

MNS, ABO, P1PK/Globoside(P), ABO, Kidd, Ii, Rh, Kell, Antigens of high prevalence, Lewis, HLA, Duffy, LuthAntigens of low prevalence,  and Platelet-specific.

Role of Blood Groups in Transfusion

Antigen prevalence and Immunogenicity 

BLOOD GROUP IMMUNOLOGY

This part is divided into Immune Response, Immunoglobulins, Antigen-Antibody Interactions, and Complement.

Immune Response

B and T cells, macrophages, Primary and secondary response, and Genetics

Immunoglobulins 

Biologic and physical properties, Structure, and Classes and subclasses

Antigen-Antibody Interactions

Testing (Principles and Methods), Principles 

Complement

Biologic properties, Classical and alternative pathway mechanisms 

Physiology And Pathophysiology

This content area is divided into five-part Physiology of Blood, Hemostasis and Coagulation, Hemolytic Disease of the Fetus and Newborn, Anemias, and Transplantation

Physiology of Blood

Composition and function of blood (Normal function, Abnormal physiology), Circulation and blood volume, Cell metabolism, and Cell survival.

Hemostasis and Coagulation 

Platelet functions and disorders, Coagulation factors and disorders

Hemolytic Disease of the Fetus and Newborn

Pathophysiology, Prevention, Treatment, and Detection 

Anemias

Congenital and acquired (Detection, Pathophysiology, Treatment), Immune hemolytic anemias: warm, cold, drug-induced (Detection, Pathophysiology, and Treatment)

Transplantation

Hematopoietic progenitor cell (HPC) and Solid organ. 

Serologic And Molecular Testing

It has five-part Routine Tests, Reagents, Application of Special Tests and Reagents, Leukocyte/Platelet Testing, and Quality Assurance.

Routine Tests

Compatibility tests (Crossmatch, Antibody detection), Antibody identification/clinical significance, Blood grouping tests, and Direct antiglobulin testing.

Reagents

Antiglobulin sera, Reagent red cells, and Blood grouping sera

Application of Special Tests and Reagents

Enzymes, Adsorptions,  Lectins, Enhancement media, Cell separations, Titrations, Elutions, ELISA, Chloroquine diphosphate, .Molecular techniques, Use of thiol reagents, Immunofluorescence, Solid phase, Column agglutination test, Neutralization/inhibition, and EDTA glycine-acid.

Leukocyte/Platelet Testing

Platelet testing and Cytotoxicity 

Quality Assurance 

Blood samples, Test procedures, and Reagents 

Transfusion Practice

Component Therapy, Indications for Transfusion, Adverse Effects of Transfusion (Immunologic reactions, Transfusion-transmitted diseases, and Nonimmunologic reactions), Blood Administration and Patient Blood Management, Apheresis, and Extracorporeal Circulation.

Immunology Study Guide For MLS(ASCP) and MLS(ASCPi)

BOC divide Immunology into six–part that is Principles Of Immunology, Diseases Of The Immune System, Transplantation, Infectious Disease Serology, Serologic Procedures, And Test Results.  BOC exam chooses 5-10% of questions from this content area.

Detail of Immunology Study Guide that is recommended by BOC.

Principles Of Immunology

This content area is divided into six-part including Immune System Physiology, Immunoglobulins, Antigen-Antibody Interactions, and Complement.

Immune System Physiology

Primary and secondary response, Genetics and B and T cells, macrophages

Immunoglobulins

Classes and subclasses, Biologic and physical properties, and Structure

Antigen-Antibody Interactions

Testing (Principles, Methods) and Principles

Complement

Biologic Properties and Classical and Alternative pathway mechanisms

Diseases Of The Immune System

Diseases Of The Immune System have four categories including Autoimmunity, Hypersensitivity, Immunoproliferative Diseases, and Immunodeficiency.

Autoimmunity

 Organ-specific (e.g., Graves disease) and Systemic (e.g., SLE)

Hypersensitivity

Type I, II, III and IV

Immunoproliferative Diseases

Monoclonal gammopathies (e.g., Waldenström macroglobulinemia, plasma cell myeloma) 

Immunodeficiency

Acquired (e.g., HIV) and Hereditary (e.g., SCID)

Transplantation

HLA Typing,  Graft-versus-host Disease, and  Tumor Immunology

Infectious Disease Serology

Stages of Infection of Treponema pallidum and Borrelia burgdorferi, Clinical Significance and Epidemiology of Viral Pathogens (e.g., hepatitis [A, B, C], HIV, HIV, EBV, HIV, measles, rubella) and Tuberculosis Infection (e.g., interferon-gamma release assay, PPD)

Serologic Procedures

ANA, Rheumatoid Factor, Thyroid Antibodies, Nontreponemal Syphilis Testing (e.g., RPR), Labeled Immunoassays (e.g., ELISA), Immunofluorescence, Cytokine Testing, and Treponemal Syphilis Testing (e.g., MHATP).

Test Results

 Interpretation, Disease State Correlation, and Confirmatory Testing 

Urinalysis and Body Fluids Study Guide For MLS(ASCP) and MLS(ASCPi)

According to BOC, Urinalysis and Body fluid exam content areas are divided into two-part including URINALYSIS and BODY FLUIDS (e.g., Feces, CSF, Synovial,  Amniotic, Serous, Semen,). 5-10% question of MLS(ASCP) and MLS(ASCPi) exam are choose from this content area.

Urinalysis and Body Fluids Study Guide detail, according to BOC.

Urinalysis

The urinalysis study guide is divided into the following part.

Physical

Specific gravity/osmolality and Color and clarity

Chemical

Confirmatory tests and Reagent strip 

Microscopic

Cells, Artifacts, Contaminants, Microorganisms, Crystals, and Casts. 

Renal Physiology

Disease States

BODY FLUIDS

e.g., Feces, CSF, Synovial, Amniotic, Serous, Semen.

Physical, Disease States, Chemical, Physiology, and Microscopic

Laboratory Operations Study Guide For MLS(ASCP) and MLS(ASCPi)

BOC divides Laboratory Operations into six- categories that are Quality Assessment/Troubleshooting, Safety, Laboratory Mathematics, Manual/Automated Methodology and Instrumentation, Basic Management Principles, And Education Principles. 5 -10% of exam questions are select from the Laboratory Operation content area.

Further details of Laboratory Operation study guide according to BOC.

Quality Assessment/Troubleshooting

Regulation (e.g., proficiency testing, accreditation standard, competency assessment), Compliance, Point-of-care Testing (POCT), Quality Control, and Preanalytical, Postanalytical, and Analytical.

Safety

• Safety Programs and Practices: Packaging and transportation of specimens and microorganisms, Safety data sheets (SDS) for chemicals and reagents, Safe work practices, Prevention of infection with bloodborne pathogens, and Use of personal protective equipment (PPE)
• Emergency Procedures (e.g., splashes to mucous membranes, needlesticks, fire)

Laboratory Mathematics 

Concentration, Dilutions, and Volume, Specificity, Sensitivity, and Predictive Value, Standard Curves, Mean, Median, Mode, and Confidence Intervals, and Normality, Molarity.

Manual/Automated Methodology And Instrumentation

Basic Laboratory Equipment, Hematology Instrumentation, Fluorometry, Osmometry, Electrophoresis, Molecular Methods, Electrochemistry, Mass Spectrometry, Nephelometry, Automated Microbiology Processors, Chromatography, Flow Cytometry, and Spectrophotometry, and Photometry.

Basic Management Principles

Education Principles

MLSIA Study Guide Premium Edition For MLS ASCP & MLS ASCPi Certification

To become a medical laboratory scientist, candidates must have excellent study material for this challenging exam preparation. In this regard, the MLSIA study material is an exclusive learning source for applicants who join the 4×4 MLS ASCP Prep Course package.

The MLSIA Study Guide Premium Edition by MLSi ACADEMY for the BOC exam offers comprehensive and complete information that is necessary to cope with exam challenges.

The MLSIA Study Guide is formulated based on the following:

1. Exam content areas mentioned in the MLS ASCP study guide,
2. BOC exam questions
3. BOC recommended reading list
4. Experience of MLSIA stuff members who passed more than one exam in all categories including, MLS ASCP, specialist and technologist, and technician exams.

The guide has the following advantages:

Conclusive

To pass the MLS ASCP exam, candidates need immaculate study material that covers the wide syllabus of this exam. MLSIA learning materials are conclusive, that cover all exam content areas, including immunology, clinical chemistry, blood bank, hematology, microbiology, and urine & body fluids.

Comprehensive

Comprehensive learning material offers all the essential details to pass the exam. This is why; candidates have always preferred to opt for a comprehensive study material than an extensive one. MLSIA offers comprehensive learning materials that can comprehend the vast content of exams concisely and push away all confusion related to the syllabus.

All-in-One Option

Many study materials are available for candidates for exam preparation. These study materials offer unnecessary detail as well as essential ones_ this extensive information blurs the reader's mind. MLSIA presents All-in-one option study material that covers all required and valuable information. Therefore candidates need not purchase anyone else study martial after picking the MLSIA.

Affordable

Due to a lack of knowledge about the study material, sometimes candidates purchase more than one or more expensive study materials for exams. Hence, applicants must search for the best and most affordable study materials before purchasing. MLSIA could be the best destination for those candidates who are searching for reasonable and conclusive study material. 

Easy to Understand

It is not child's play to pass the MLS ASCP exam without any clarification. BOC offers an ample study guide for exam preparation, and no one cannot pass this exam without choosing any outstanding learning material. MLSIA study materials are easy to understand and solve all exam confusion appropriately. Therefore candidates must choose the MLSIA study material instead of choosing more than one.

Flexible format

MLSIA study material attempts to clear candidates’ all confusion with their flexible format (Video, PDF). Readers can watch the video if they cannot understand the reading content. 

Get The MLSIA Study Guide for MLS ASCP/ ASCPi Here?

MLS ASCP Study Reading List for MLS ASCP and MLS ASCPi

BOC recommended study resources for exam preparation that is called MLS ASCP Study Reading List. This reading list suggests specific textbook, online Journals, and associations to cover exam content including chemistry, blood bank, immunology & serology, urinalysis and body fluids, microbiology, and hematology.

How to Study for MLS ASCP Exam?

MLS ASCP Exam has always been a challenge for candidates and they apply all tips and trick to pass this difficult exam. Some authentic ways are described below to overcome the Exam's difficulties.

FAQ for MLS ASCP Study Guide

Source: ASC BOC Content Guideline here.